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KMID : 0360220080490091525
Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 9 p.1525 ~ p.1531
Corneal Opacity Caused by LASEK with Improper High-concentrated Mitomycin-C
Kim Su-Jin

Lee Jong-Soo
Lee Min-Ho
Kim Eun-Hee
Abstract
Purpose: To report a case of corneal opacity with postoperative changes of topographic features and visual acuity after laser subepithelial keratomileusis (LASEK) treated with an improper concentration of mitomycin-C.

Case summary: A 25-year-old female patient who experienced corneal opacity after LASEK treated with mitomycin-C was evaluated for changes in corneal opacity by photography, central corneal power by Orb scan ¥±z, and best corrected visual acuity (BCVA) over the period of 1 year. The corneal epithelial defect was completely healed 2 weeks after the LASEK operation. Subepithelial and stromal opacity decreased over time, but her cornea did not return to normal. BCVA was 20/25 in the right eye and 20/20 in the left eye at postoperative 1 year, but stromal opacity remained.

Conclusions: An improper concentration of mitomycin-C during LASEK could result in corneal opacity. Long time is needed to recover visual acuity and a normal corneal structure. J Korean Ophthalmol Soc 2008;49(9):1525-1531
KEYWORD
Cornealopacity, LASEK, Mitomycin-C
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